PSII-1 An Evaluation of a Nutrient Drench Administered to Calves at Arrival into the Feedlot on Subsequent Health Status and Assessment of Immune Status with a Rapid Immunity Test

Abstract A functionally effective immune system is required to maintain health and resist disease challenges for cattle received into the feedlot. Transport a primary stressor that can decrease trace mineral status impair function. The objectives of this study were 1) evaluate drench providing key supplemental minerals (Cu, Mn, Se Zn) administered at arrival feedlot on subsequent morbidity 2) application novel technology assessing in stressed calves risk respiratory (BRD). From October through December 2021, 20 loads Angus x Holstein heifers (n=1,988; 218± 2.7 kg) transported from calf rearing facility northwest OH commercial southwest NE. At initial processing, individually identified weighed common processing protocol. Based individual ear tag number either provided no (even-numbered tags; CONTROL) or 45 mL nutrient (odd-numbered Profusion™, Zinpro Corporation, Eden Prairie, MN). Across 10 blood samples collected approximately 300 animals measurement humoral immunity (D2Dx™; Nano Discovery Inc., Orlando, FL). Subsequent was monitored throughout weeks following arrival. Data analyzed using Proc Mixed Glimmix with fixed effects treatment load heifer as experimental unit. Morbidity each classified based whether animal subsequently pulled treated diagnosed disease. Initial BW did not differ between treatments (P ≥ 0.67); however, varied among ≤ 0.01) lower BRD. Reported mortality all causes minimal analyzed. Respiratory cause disease; incidence affected 0.55) by (21.1% vs. 23.5% CONTROL PROFUSION, respectively). Time first recorded (range: 4 – 35 d) mean median value 26 21 d respectively effects. Measured D2Dx scores 0.43) assigned PROFUSION treatments; different 0.01). In BRD, 23% 0.07; score =0.0138) compared non-BRD (D2Dx = 0.0180). These results suggest administration may have been optimum observed patterns especially Th-1 thereby be more susceptible clinical